Effects of piperitenone oxide on the intestinal smooth muscle of the guinea pig

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Effects of piperitenone oxide on the intestinal smooth muscle of the guinea pig.

We investigated the effects of piperitenone oxide (PO), a major constituent of the essential oil of Mentha x villosa, on the guinea pig ileum. PO (30 to 740 micrograms/ml) relaxed basal tonus without significantly altering the resting membrane potential. In addition, PO relaxed preparations precontracted with either 60 mM K+ or 5 mM tetraethylammonium in a concentration-dependent manner. At con...

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ژورنال

عنوان ژورنال: Brazilian Journal of Medical and Biological Research

سال: 1997

ISSN: 0100-879X

DOI: 10.1590/s0100-879x1997000600014